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[PubMed - in process] Anti-angiogenic and inhibitory activity
PMID: 15180575 [PubMed - in process] Anti-angiogenic and inhibitory activity on inducible nitric oxide production of the mushroom Ganoderma lucidum.

Song YS, Kim SH, Sa JH, Jin C, Lim CJ, Park EH.

Bioanalysis and Biotransformation Research Center, Korea Institute of Science and Technology, PO Box 131, Seoul 130-650, South Korea.

Fresh fruit bodies of Ganoderma lucidum were extracted with 70% ethanol at room temperature. The extract (GL) showed significant anti-angiogenic activity, which was detected using a chick embryo chorioallantoic membrane assay. GL significantly inhibited LPS-induced NO production in RAW 264.7 macrophages. These results support the anti-tumor effect of Ganoderma lucidum.
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